I lead compartmentalized life, anyway; but when I open e-mail, I like to know what my mindset and attitude are going to be.
One hardly need know what time a friend's birthday party is or how a cousin is getting along while they're Tracking the Market or Reviewing an Alert! Talk about a break in concentration!
My personal e-mail addresses will never have any Market/Business info in them. Conversely, business-oriented e-mail addresses will never have a buddy saying "Hey" or asking "What's hap?". I'd never think of opening addresses Friends & Family send to while I'm doing Market Research. But if I am in need of a smile, Friends & Family news is just a click away.
Note: Best not to even give your f&f R&D addresses.

(Oh yeah kids, before I get those "Huh?" Comments I find exasperating; KISS has nothing to do with the band. [link])
And, after all that, you may need this: NOTIFIER 2 (even with your current e-mail provider)